Sunday, March 14, 2010

Bismuth toxicity

From UPCC, published by the Utah Poison Control Center: Bismuth toxicity was common when soluble bismuth salts were used in the treatment of syphilis and amebiasis. Symptoms included fever, weakness, jaundice, diarrhea, stomatitis, and blackening of the oral mucosa... Between 1973 and 1980 approximately 1000 cases of bismuth related neurotoxicity and over 70 deaths were reported in France... Today bismuth salts are primarily used for the treatment of gastrointestinal (GI) illnesses. Toxicity is uncommon from oral administration of over-the-counter preparations (Table 1) but the potential still exists...
============================================
If you are interested in risks potentially posed to human health by exposure to bismuth or its compounds, please click here: TOX-PROFILE: Bismuth and Compounds, CAS No. 7440-35-9 to go to the purchase page for the Bismuth Tox-Profile prepared by Dr. Michaels. This toxicological profile is offered for sale by the Center for Health Risk Assessment and Management.
============================================